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EHMT2 inhibitor BIX-01294 induces apoptosis through PMAIP1-USP9X-MCL1 axis in human bladder cancer cells

BIX-01294, an euchromatic histone-lysine N-methyltransferase 2 (EHMT2) inhibitor, has been reported to induce apoptosis in human neuroblastoma cells and inhibit the proliferation of bladder cancer cells. However, the definite mechanism of the apoptosis mediated by BIX-01294 in bladder cancer cells r...

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Detalles Bibliográficos
Autores principales:	Cui, Jing, Sun, Wendong, Hao, Xuexi, Wei, Minli, Su, Xiaonan, Zhang, Yajing, Su, Ling, Liu, Xiangguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326523/ https://www.ncbi.nlm.nih.gov/pubmed/25685062 http://dx.doi.org/10.1186/s12935-014-0149-x

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