An Endotoxin Tolerance Signature Predicts Sepsis and Organ Dysfunction at Initial Clinical Presentation

BACKGROUND: Sepsis involves aberrant immune responses to infection, but the exact nature of this immune dysfunction remains poorly defined. Bacterial endotoxins like lipopolysaccharide (LPS) are potent inducers of inflammation, which has been associated with the pathophysiology of sepsis, but repeat...

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Detalles Bibliográficos
Autores principales: Pena, Olga M., Hancock, David G., Lyle, Ngan H., Linder, Adam, Russell, James A., Xia, Jianguo, Fjell, Christopher D., Boyd, John H., Hancock, Robert E.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326653/
https://www.ncbi.nlm.nih.gov/pubmed/25685830
http://dx.doi.org/10.1016/j.ebiom.2014.10.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326653/
https://www.ncbi.nlm.nih.gov/pubmed/25685830
http://dx.doi.org/10.1016/j.ebiom.2014.10.003

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