Cargando…
DC-SCRIPT is a novel regulator of the tumor suppressor gene CDKN2B and induces cell cycle arrest in ERα-positive breast cancer cells
Breast cancer is one of the most common causes of cancer-related deaths in women. The estrogen receptor (ERα) is well known for having growth promoting effects in breast cancer. Recently, we have identified DC-SCRIPT (ZNF366) as a co-suppressor of ERα and as a strong and independent prognostic marke...
Autores principales: | Ansems, Marleen, Søndergaard, Jonas Nørskov, Sieuwerts, Anieta M., Looman, Maaike W. G., Smid, Marcel, de Graaf, Annemarie M. A., de Weerd, Vanja, Zuidscherwoude, Malou, Foekens, John A., Martens, John W. M., Adema, Gosse J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326655/ https://www.ncbi.nlm.nih.gov/pubmed/25663546 http://dx.doi.org/10.1007/s10549-015-3281-y |
Ejemplares similares
-
Clinical significance of the nuclear receptor co-regulator DC-SCRIPT in breast cancer: an independent retrospective validation study
por: Sieuwerts, Anieta M, et al.
Publicado: (2010) -
Dendritic Cells Actively Limit Interleukin-10 Production Under Inflammatory Conditions via DC-SCRIPT and Dual-Specificity Phosphatase 4
por: Søndergaard, Jonas Nørskov, et al.
Publicado: (2018) -
High TWIST1 mRNA expression is associated with poor prognosis in lymph node-negative and estrogen receptor-positive human breast cancer and is co-expressed with stromal as well as ECM related genes
por: Riaz, Muhammad, et al.
Publicado: (2012) -
DC-STAMP knock-down deregulates cytokine production and T-cell stimulatory capacity of LPS-matured dendritic cells
por: Sanecka, Anna, et al.
Publicado: (2011) -
Mitochondrial DNA content in breast cancer: Impact on in vitro and in vivo phenotype and patient prognosis
por: Weerts, Marjolein J.A., et al.
Publicado: (2016)