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Biophysical Studies on Interactions and Assembly of Full-size E3 Ubiquitin Ligase: SUPPRESSOR OF CYTOKINE SIGNALING 2 (SOCS2)-ELONGIN BC-CULLIN 5-RING BOX PROTEIN 2 (RBX2)

The multisubunit cullin RING E3 ubiquitin ligases (CRLs) target post-translationally modified substrates for ubiquitination and proteasomal degradation. The suppressors of cytokine signaling (SOCS) proteins play important roles in inflammatory processes, diabetes, and cancer and therefore represent...

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Detalles Bibliográficos
Autores principales:	Bulatov, Emil, Martin, Esther M., Chatterjee, Sneha, Knebel, Axel, Shimamura, Satoko, Konijnenberg, Albert, Johnson, Clare, Zinn, Nico, Grandi, Paola, Sobott, Frank, Ciulli, Alessio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2015
Materias:	Molecular Biophysics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326827/ https://www.ncbi.nlm.nih.gov/pubmed/25505247 http://dx.doi.org/10.1074/jbc.M114.616664

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