Cargando…

Endoplasmic reticulum stress activates telomerase

Telomerase contributes to cell proliferation and survival through both telomere-dependent and telomere-independent mechanisms. In this report, we discovered that endoplasmic reticulum (ER) stress transiently activates the catalytic components of telomerase (TERT) expression in human cancer cell line...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Junzhi, Mao, Beibei, Zhou, Qi, Ding, Deqiang, Wang, Miao, Guo, Peng, Gao, Yuhao, Shay, Jerry W, Yuan, Zengqiang, Cong, Yu-Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Short Takes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326870/ https://www.ncbi.nlm.nih.gov/pubmed/24119029 http://dx.doi.org/10.1111/acel.12161

Ejemplares similares

Telomerase reverse transcriptase in the regulation of gene expression
por: Zhou, Junzhi, et al.
Publicado: (2014)

Base excision repair but not DNA double‐strand break repair is impaired in aged human adipose‐derived stem cells
por: Zhang, Haiping, et al.
Publicado: (2019)

Shared signatures of social stress and aging in peripheral blood mononuclear cell gene expression profiles
por: Snyder-Mackler, Noah, et al.
Publicado: (2014)

Follicle-stimulating hormone promotes age-related endometrial atrophy through cross-talk with transforming growth factor beta signal transduction pathway
por: Zhang, Dan, et al.
Publicado: (2015)

Fibroblasts derived from long-lived insulin receptor substrate 1 null mice are not resistant to multiple forms of stress
por: Page, Melissa M, et al.
Publicado: (2014)

Neuronal protein with tau-like repeats (PTL-1) regulates intestinal SKN-1 nuclear accumulation in response to oxidative stress
por: Chew, Yee Lian, et al.
Publicado: (2015)

The SKN‐1/Nrf2 transcription factor can protect against oxidative stress and increase lifespan in C. elegans by distinct mechanisms
por: Tullet, Jennifer M.A., et al.
Publicado: (2017)

Central insulin‐like growth factor‐1 (IGF‐1) restores whole‐body insulin action in a model of age‐related insulin resistance and IGF‐1 decline
por: Huffman, Derek M., et al.
Publicado: (2015)

Senolytics alleviate the degenerative disorders of temporomandibular joint in old age
por: Zhou, Yueying, et al.
Publicado: (2021)

The SIRT6 activator MDL‐800 improves genomic stability and pluripotency of old murine‐derived iPS cells
por: Chen, Yu, et al.
Publicado: (2020)

Influence of cell distribution and diabetes status on the association between mitochondrial DNA copy number and aging phenotypes in the InCHIANTI study
por: Moore, Ann Zenobia, et al.
Publicado: (2017)

Mitochondrial DNA copy number and heteroplasmy load correlate with skeletal muscle oxidative capacity by P31 MR spectroscopy
por: Tian, Qu, et al.
Publicado: (2021)

Transplanting cells from old but not young donors causes physical dysfunction in older recipients
por: Wang, Binsheng, et al.
Publicado: (2020)

Tau overexpression impairs neuronal endocytosis by decreasing the GTPase dynamin 1 through the miR‐132/MeCP2 pathway
por: Xie, Ao‐Ji, et al.
Publicado: (2019)

Dysregulated homeostatic pathways in sarcopenia among frail older adults
por: Ng, Tze Pin, et al.
Publicado: (2018)

Transformation of resident notochord‐descendent nucleus pulposus cells in mouse injury‐induced fibrotic intervertebral discs
por: Au, Tiffany Y. K., et al.
Publicado: (2020)

Mitochondrial turnover in liver is fast in vivo and is accelerated by dietary restriction: application of a simple dynamic model
por: Miwa, Satomi, et al.
Publicado: (2008)

The low abundance of clonally expanded mitochondrial DNA point mutations in aged substantia nigra neurons
por: Reeve, Amy K, et al.
Publicado: (2009)

miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging
por: Hackl, Matthias, et al.
Publicado: (2010)

Age-associated mitochondrial DNA mutations lead to small but significant changes in cell proliferation and apoptosis in human colonic crypts
por: Nooteboom, Marco, et al.
Publicado: (2010)

The overexpression of major antioxidant enzymes does not extend the lifespan of mice
por: Pérez, Viviana I, et al.
Publicado: (2009)

Age-related variation in immunity in a wild mammal population
por: Nussey, Daniel H, et al.
Publicado: (2012)

Exploring mechanisms of sex differences in longevity: lifetime ovary exposure and exceptional longevity in dogs
por: Waters, David J, et al.
Publicado: (2009)

Rapamycin decreases DNA damage accumulation and enhances cell growth of WRN-deficient human fibroblasts
por: Saha, Bidisha, et al.
Publicado: (2014)

Low insulin-like growth factor-1 level predicts survival in humans with exceptional longevity
por: Milman, Sofiya, et al.
Publicado: (2014)

IGF-I regulates the age-dependent signaling peptide humanin
por: Lee, Changhan, et al.
Publicado: (2014)

A genomics approach identifies senescence-specific gene expression regulation
por: Lackner, Daniel H, et al.
Publicado: (2014)

Deleted in Breast Cancer 1 regulates cellular senescence during obesity
por: Escande, Carlos, et al.
Publicado: (2014)

SIRT1 but not its increased expression is essential for lifespan extension in caloric-restricted mice
por: Mercken, Evi M, et al.
Publicado: (2014)

Do altered energy metabolism or spontaneous locomotion ‘mediate’ decelerated senescence?
por: Arum, Oge, et al.
Publicado: (2015)

The rejuvenating effect of pregnancy on muscle regeneration
por: Falick Michaeli, Tal, et al.
Publicado: (2015)

Paternal age and telomere length in twins: the germ stem cell selection paradigm
por: Hjelmborg, Jacob B, et al.
Publicado: (2015)

Haploinsufficiency of myostatin protects against aging-related declines in muscle function and enhances the longevity of mice
por: Mendias, Christopher L, et al.
Publicado: (2015)

The life-extending effect of dietary restriction requires Foxo3 in mice
por: Shimokawa, Isao, et al.
Publicado: (2015)

Increased gene dosage of Ink4/Arf and p53 delays age-associated central nervous system functional decline
por: Carrasco-Garcia, Estefania, et al.
Publicado: (2015)

Age‐related changes in murine myometrial transcript profile are mediated by exposure to the female sex hormones
por: Chong, Hsu P., et al.
Publicado: (2015)

Intact endothelial autophagy is required to maintain vascular lipid homeostasis
por: Torisu, Kumiko, et al.
Publicado: (2015)

Infection susceptibility and immune senescence with advancing age replicated in accelerated aging Lmna (Dhe) mice
por: Xin, Lijun, et al.
Publicado: (2015)

Increased Lipocalin-2 in the retinal pigment epithelium of Cryba1 cKO mice is associated with a chronic inflammatory response
por: Valapala, Mallika, et al.
Publicado: (2014)

Immunochip analysis identifies association of the RAD50/IL13 region with human longevity
por: Flachsbart, Friederike, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_cdjuboeh9n03iee80sf1ktog1c