Glyoxalase I reduces glycative and oxidative stress and prevents age-related endothelial dysfunction through modulation of endothelial nitric oxide synthase phosphorylation

Endothelial dysfunction is a major contributor to cardiovascular disease (CVD), particularly in elderly people. Studies have demonstrated the role of glycation in endothelial dysfunction in nonphysiological models, but the physiological role of glycation in age-related endothelial dysfunction has be...

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Detalles Bibliográficos
Autores principales: Jo-Watanabe, Airi, Ohse, Takamoto, Nishimatsu, Hiroaki, Takahashi, Masao, Ikeda, Yoichiro, Wada, Takehiko, Shirakawa, Jun-ichi, Nagai, Ryoji, Miyata, Toshio, Nagano, Tetsuo, Hirata, Yasunobu, Inagi, Reiko, Nangaku, Masaomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326886/
https://www.ncbi.nlm.nih.gov/pubmed/24612481
http://dx.doi.org/10.1111/acel.12204

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