Sulforaphane enhances progerin clearance in Hutchinson–Gilford progeria fibroblasts

Hutchinson–Gilford progeria syndrome (HGPS, OMIM 176670) is a rare multisystem childhood premature aging disorder linked to mutations in the LMNA gene. The most common HGPS mutation is found at position G608G within exon 11 of the LMNA gene. This mutation results in the deletion of 50 amino acids at...

Descripción completa

Detalles Bibliográficos
Autores principales: Gabriel, Diana, Roedl, Daniela, Gordon, Leslie B, Djabali, Karima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326906/
https://www.ncbi.nlm.nih.gov/pubmed/25510262
http://dx.doi.org/10.1111/acel.12300

Ejemplares similares

Ejemplares similares