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Muscle ectopic fat deposition contributes to anabolic resistance in obese sarcopenic old rats through eIF2α activation

Obesity and aging are characterized by decreased insulin sensitivity (IS) and muscle protein synthesis. Intramuscular ceramide accumulation has been implicated in insulin resistance during obesity. We aimed to measure IS, muscle ceramide level, protein synthesis, and activation of intracellular sign...

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Detalles Bibliográficos
Autores principales:	Tardif, Nicolas, Salles, Jérôme, Guillet, Christelle, Tordjman, Joan, Reggio, Sophie, Landrier, Jean-François, Giraudet, Christophe, Patrac, Véronique, Bertrand-Michel, Justine, Migne, Carole, Collin, Marie-Laure, Chardigny, Jean-Michel, Boirie, Yves, Walrand, Stéphane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326920/ https://www.ncbi.nlm.nih.gov/pubmed/25139155 http://dx.doi.org/10.1111/acel.12263

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