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When man got his mtDNA deletions?

Somatic mtDNA mutations and deletions in particular are known to clonally expand within cells, eventually reaching detrimental intracellular concentrations. The possibility that clonal expansion is a slow process taking a lifetime had prompted an idea that founder mutations of mutant clones that cau...

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Detalles Bibliográficos
Autores principales: Popadin, Konstantin, Safdar, Adeel, Kraytsberg, Yevgenya, Khrapko, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326951/
https://www.ncbi.nlm.nih.gov/pubmed/24894296
http://dx.doi.org/10.1111/acel.12231