Probing the substrate specificity of Trypanosoma brucei GlcNAc-PI de-N-acetylase with synthetic substrate analogues

A series of synthetic analogues of 1-d-(2-amino-2-deoxy-α-d-glucopyranosyl)-myo-inositol 1-(1,2-di-O-hexadecanoyl-sn-glycerol 3-phosphate), consisting of 7 variants of either the d-myo-inositol, d-GlcpN or the phospholipid components, were prepared and tested as substrates and inhibitors of GlcNAc-P...

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Detalles Bibliográficos
Autores principales: Capes, Amy S., Crossman, Arthur, Urbaniak, Michael D., Gilbert, Sophie H., Ferguson, Michael A. J., Gilbert, Ian H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2014
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326964/
https://www.ncbi.nlm.nih.gov/pubmed/24519084
http://dx.doi.org/10.1039/c3ob42164c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326964/
https://www.ncbi.nlm.nih.gov/pubmed/24519084
http://dx.doi.org/10.1039/c3ob42164c

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