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Probing the substrate specificity of Trypanosoma brucei GlcNAc-PI de-N-acetylase with synthetic substrate analogues
A series of synthetic analogues of 1-d-(2-amino-2-deoxy-α-d-glucopyranosyl)-myo-inositol 1-(1,2-di-O-hexadecanoyl-sn-glycerol 3-phosphate), consisting of 7 variants of either the d-myo-inositol, d-GlcpN or the phospholipid components, were prepared and tested as substrates and inhibitors of GlcNAc-P...
Autores principales: | Capes, Amy S., Crossman, Arthur, Urbaniak, Michael D., Gilbert, Sophie H., Ferguson, Michael A. J., Gilbert, Ian H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326964/ https://www.ncbi.nlm.nih.gov/pubmed/24519084 http://dx.doi.org/10.1039/c3ob42164c |
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