Cargando…
Rare Variation Facilitates Inferences of Fine-Scale Population Structure in Humans
Understanding the genetic structure of human populations has important implications for the design and interpretation of disease mapping studies and reconstructing human evolutionary history. To date, inferences of human population structure have primarily been made with common variants. However, re...
Autores principales: | O’Connor, Timothy D., Fu, Wenqing, Mychaleckyj, Josyf C., Logsdon, Benjamin, Auer, Paul, Carlson, Christopher S., Leal, Suzanne M., Smith, Joshua D., Rieder, Mark J., Bamshad, Michael J., Nickerson, Deborah A., Akey, Joshua M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327153/ https://www.ncbi.nlm.nih.gov/pubmed/25415970 http://dx.doi.org/10.1093/molbev/msu326 |
Ejemplares similares
-
Fine-Scale Patterns of Population Stratification Confound Rare Variant Association Tests
por: O’Connor, Timothy D., et al.
Publicado: (2013) -
Genome-Wide Analysis in Brazilians Reveals Highly Differentiated Native American Genome Regions
por: Mychaleckyj, Josyf C., et al.
Publicado: (2017) -
Enhancers Facilitate the Birth of De Novo Genes and Gene Integration into Regulatory Networks
por: Majic, Paco, et al.
Publicado: (2020) -
Analysis of 6,515 exomes reveals a recent origin of most human protein-coding variants
por: Fu, Wenqing, et al.
Publicado: (2012) -
Evolution of Human-Specific Alleles Protecting Cognitive Function of Grandmothers
por: Saha, Sudeshna, et al.
Publicado: (2022)