ESCRT-0 marks an APPL1-independent transit route for EGFR between the cell surface and the EEA1-positive early endosome

Endosomal sorting complexes required for transport (ESCRT)-0 sorts ubiquitylated EGFR within the early endosome so that the receptor can be incorporated into intralumenal vesicles. An important question is whether ESCRT-0 acts solely upon EGFR that has already entered the vacuolar early endosome (ch...

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Detalles Bibliográficos
Autores principales: Flores-Rodriguez, Neftali, Kenwright, David A., Chung, Pei-Hua, Harrison, Andrew W., Stefani, Flavia, Waigh, Thomas A., Allan, Victoria J., Woodman, Philip G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327388/
https://www.ncbi.nlm.nih.gov/pubmed/25588841
http://dx.doi.org/10.1242/jcs.161786

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