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Neuroprotective strategies against calpain-mediated neurodegeneration

Calpains are calcium-dependent proteolytic enzymes that have deleterious effects on neurons upon their pathological over-activation. According to the results of numerous studies to date, there is no doubt that abnormal calpain activation triggers activation and progression of apoptotic processes in...

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Detalles Bibliográficos
Autores principales: Yildiz-Unal, Aysegul, Korulu, Sirin, Karabay, Arzu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327398/
https://www.ncbi.nlm.nih.gov/pubmed/25709452
http://dx.doi.org/10.2147/NDT.S78226