BIOCOMPATIBILITY OF ACELLULAR DERMAL MATRIX GRAFT EVALUATED IN CULTURE OF MURINE MACROPHAGES

The acellular dermal matrix allograft has been used as an alternative to autogenous palatal mucosal graft. The aim of this study was the evaluation of the biocompatibility of an acellular dermal matrix (AlloDerm®) in culture of macrophages. For hydrogen peroxidase determination we used the method of...

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Detalles Bibliográficos
Autores principales: Vendramini, Ana Paula, Melo, Rafaela Fernanda, Marcantonio, Rosemary Adriana Chiérici, Carlos, Iracilda Zepone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculdade de Odontologia de Bauru da Universidade de São Paulo 2006
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327444/
https://www.ncbi.nlm.nih.gov/pubmed/19089033
http://dx.doi.org/10.1590/S1678-77572006000200001
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author Vendramini, Ana Paula
Melo, Rafaela Fernanda
Marcantonio, Rosemary Adriana Chiérici
Carlos, Iracilda Zepone
author_facet Vendramini, Ana Paula
Melo, Rafaela Fernanda
Marcantonio, Rosemary Adriana Chiérici
Carlos, Iracilda Zepone
author_sort Vendramini, Ana Paula
collection PubMed
description The acellular dermal matrix allograft has been used as an alternative to autogenous palatal mucosal graft. The aim of this study was the evaluation of the biocompatibility of an acellular dermal matrix (AlloDerm®) in culture of macrophages. For hydrogen peroxidase determination we used the method of Pick & Kesari, and the Griess method for nitric oxide determination,. Statistical analysis showed no significant difference (p ≤ 0,05) in the release of nitric oxide and hydrogen peroxide by the macrophages exposed to acellular dermal matrix and the negative control. The results suggest that acellular dermal matrix did not activate the cell inflammatory response.
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spelling pubmed-43274442015-04-23 BIOCOMPATIBILITY OF ACELLULAR DERMAL MATRIX GRAFT EVALUATED IN CULTURE OF MURINE MACROPHAGES Vendramini, Ana Paula Melo, Rafaela Fernanda Marcantonio, Rosemary Adriana Chiérici Carlos, Iracilda Zepone J Appl Oral Sci Original Article The acellular dermal matrix allograft has been used as an alternative to autogenous palatal mucosal graft. The aim of this study was the evaluation of the biocompatibility of an acellular dermal matrix (AlloDerm®) in culture of macrophages. For hydrogen peroxidase determination we used the method of Pick & Kesari, and the Griess method for nitric oxide determination,. Statistical analysis showed no significant difference (p ≤ 0,05) in the release of nitric oxide and hydrogen peroxide by the macrophages exposed to acellular dermal matrix and the negative control. The results suggest that acellular dermal matrix did not activate the cell inflammatory response. Faculdade de Odontologia de Bauru da Universidade de São Paulo 2006-04 /pmc/articles/PMC4327444/ /pubmed/19089033 http://dx.doi.org/10.1590/S1678-77572006000200001 Text en http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Vendramini, Ana Paula
Melo, Rafaela Fernanda
Marcantonio, Rosemary Adriana Chiérici
Carlos, Iracilda Zepone
BIOCOMPATIBILITY OF ACELLULAR DERMAL MATRIX GRAFT EVALUATED IN CULTURE OF MURINE MACROPHAGES
title BIOCOMPATIBILITY OF ACELLULAR DERMAL MATRIX GRAFT EVALUATED IN CULTURE OF MURINE MACROPHAGES
title_full BIOCOMPATIBILITY OF ACELLULAR DERMAL MATRIX GRAFT EVALUATED IN CULTURE OF MURINE MACROPHAGES
title_fullStr BIOCOMPATIBILITY OF ACELLULAR DERMAL MATRIX GRAFT EVALUATED IN CULTURE OF MURINE MACROPHAGES
title_full_unstemmed BIOCOMPATIBILITY OF ACELLULAR DERMAL MATRIX GRAFT EVALUATED IN CULTURE OF MURINE MACROPHAGES
title_short BIOCOMPATIBILITY OF ACELLULAR DERMAL MATRIX GRAFT EVALUATED IN CULTURE OF MURINE MACROPHAGES
title_sort biocompatibility of acellular dermal matrix graft evaluated in culture of murine macrophages
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327444/
https://www.ncbi.nlm.nih.gov/pubmed/19089033
http://dx.doi.org/10.1590/S1678-77572006000200001
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