Cargando…

A small molecule inhibitor of dengue virus type 2 protease inhibits the replication of all four dengue virus serotypes in cell culture

BACKGROUND: Dengue has emerged as the most significant of arboviral diseases in the 21st century. It is endemic to >100 tropical and sub-tropical countries around the world placing an estimated 3.6 billion people at risk. It is caused by four genetically similar but antigenically distinct, seroty...

Descripción completa

Detalles Bibliográficos
Autores principales:	Raut, Rajendra, Beesetti, Hemalatha, Tyagi, Poornima, Khanna, Ira, Jain, Swatantra K, Jeankumar, Variam U, Yogeeswari, Perumal, Sriram, Dharmarajan, Swaminathan, Sathyamangalam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327787/ https://www.ncbi.nlm.nih.gov/pubmed/25886260 http://dx.doi.org/10.1186/s12985-015-0248-x

Ejemplares similares

An adenovirus prime/plasmid boost strategy for induction of equipotent immune responses to two dengue virus serotypes
por: Khanam, Saima, et al.
Publicado: (2007)

Chimeric Hepatitis B core antigen virus-like particles displaying the envelope domain III of dengue virus type 2
por: Arora, Upasana, et al.
Publicado: (2012)

Pichia pastoris-expressed dengue 3 envelope-based virus-like particles elicit predominantly domain III-focused high titer neutralizing antibodies
por: Tripathi, Lav, et al.
Publicado: (2015)

Dengue and Zika virus infections are enhanced by live attenuated dengue vaccine but not by recombinant DSV4 vaccine candidate in mouse models
por: Shukla, Rahul, et al.
Publicado: (2020)

Cissampelos pareira Linn: Natural Source of Potent Antiviral Activity against All Four Dengue Virus Serotypes
por: Sood, Ruchi, et al.
Publicado: (2015)

Dengue-specific subviral nanoparticles: design, creation and characterization
por: Khetarpal, Niyati, et al.
Publicado: (2013)

Pichia pastoris-Expressed Dengue 2 Envelope Forms Virus-Like Particles without Pre-Membrane Protein and Induces High Titer Neutralizing Antibodies
por: Mani, Shailendra, et al.
Publicado: (2013)

Adenovirus Delivered Short Hairpin RNA Targeting a Conserved Site in the 5′ Non-Translated Region Inhibits All Four Serotypes of Dengue Viruses
por: Korrapati, Anil Babu, et al.
Publicado: (2012)

Virus-like particles derived from Pichia pastoris-expressed dengue virus type 1 glycoprotein elicit homotypic virus-neutralizing envelope domain III-directed antibodies
por: Poddar, Ankur, et al.
Publicado: (2016)

Evaluation of envelope domain III-based single chimeric tetravalent antigen and monovalent antigen mixtures for the detection of anti-dengue antibodies in human sera
por: Batra, Gaurav, et al.
Publicado: (2011)

Casamino acids facilitate the secretion of recombinant dengue virus serotype-3 envelope domain III in Pichia pastoris
por: Kaushik, Neha, et al.
Publicado: (2016)

A tetravalent virus-like particle vaccine designed to display domain III of dengue envelope proteins induces multi-serotype neutralizing antibodies in mice and macaques which confer protection against antibody dependent enhancement in AG129 mice
por: Ramasamy, Viswanathan, et al.
Publicado: (2018)

Dengue virus antibody database: Systematically linking serotype-specificity with epitope mapping in dengue virus
por: Chaudhury, Sidhartha, et al.
Publicado: (2017)

Dengue Virus Serotype 3, Karachi, Pakistan
por: Jamil, Bushra, et al.
Publicado: (2007)

Dengue envelope-based ‘four-in-one’ virus-like particles produced using Pichia pastoris induce enhancement-lacking, domain III-directed tetravalent neutralising antibodies in mice
por: Rajpoot, Ravi Kant, et al.
Publicado: (2018)

High performance dengue virus antigen-based serotyping-NS1-ELISA (plus): A simple alternative approach to identify dengue virus serotypes in acute dengue specimens
por: Prommool, Tanapan, et al.
Publicado: (2021)

Dengue Virus Serotype 4, Northeastern Peru, 2008
por: Forshey, Brett M., et al.
Publicado: (2009)

Dengue Virus Serotype 4, Roraima State, Brazil
por: Acosta, Pablo Oscar Amézaga, et al.
Publicado: (2011)

Dengue Virus Serotype 4, Roraima State, Brazil
por: Temporão, José Gomes, et al.
Publicado: (2011)

Concurrent infections of dengue virus serotypes in Bali, Indonesia
por: Masyeni, Sri, et al.
Publicado: (2019)

In-silico Antigenicity Determination and Clustering of Dengue Virus Serotypes
por: Qiu, Jingxuan, et al.
Publicado: (2018)

Acute macular neuroretinopathy in dengue virus serotype 1
por: Guardiola, Gabriel A., et al.
Publicado: (2022)

Reemergence of Dengue Virus Serotype 3, Brazil, 2023
por: Naveca, Felipe Gomes, et al.
Publicado: (2023)

Mathematical modeling of Dengue virus serotypes propagation in Mexico
por: Sánchez-González, Gilberto, et al.
Publicado: (2023)

Occurrence of 4 Dengue Virus Serotypes and Chikungunya Virus in Kilombero Valley, Tanzania, During the Dengue Outbreak in 2018
por: Chipwaza, Beatrice, et al.
Publicado: (2020)

Sinococuline, a bioactive compound of Cocculus hirsutus has potent anti-dengue activity
por: Shukla, Rahul, et al.
Publicado: (2023)

Dengue Reporter Virus Particles for Measuring Neutralizing Antibodies against Each of the Four Dengue Serotypes
por: Mattia, Kimberly, et al.
Publicado: (2011)

Dengue Virus Serotype 4 Is Responsible for the Outbreak of Dengue in East Java City of Jember, Indonesia
por: Aryati, Aryati, et al.
Publicado: (2020)

Dengue Fever Outbreaks Caused by Varied Serotype Dengue Virus — Guangdong Province, China, 2019
por: Wu, De, et al.
Publicado: (2020)

DengueSeq: A pan-serotype whole genome amplicon sequencing protocol for dengue virus
por: Vogels, Chantal B.F., et al.
Publicado: (2023)

Circulation of Dengue Virus Serotype 1 Genotype V and Dengue Virus Serotype 2 Genotype III in Tocantins State, Northern Brazil, 2021–2022
por: de Souza, Ueric José Borges, et al.
Publicado: (2023)

Neutralization of Dengue Virus Serotypes by Sera from Dengue-Infected Individuals Is Preferentially Directed to Heterologous Serotypes and Not against the Autologous Serotype Present in Acute Infection
por: Auerswald, Heidi, et al.
Publicado: (2021)

Correlation of Serotype-Specific Dengue Virus Infection with Clinical Manifestations
por: Halsey, Eric S., et al.
Publicado: (2012)

Imported Dengue Virus Serotype 3, Yemen to Italy, 2010
por: Ravanini, Paolo, et al.
Publicado: (2011)

Phylogeography of Dengue Virus Serotype 4, Brazil, 2010–2011
por: Nunes, Marcio Roberto Teixeira, et al.
Publicado: (2012)

Serotyping dengue virus with isothermal amplification and a portable sequencer
por: Yamagishi, Junya, et al.
Publicado: (2017)

Emergence of Dengue Virus Serotype 2 Cosmopolitan Genotype, Brazil
por: Giovanetti, Marta, et al.
Publicado: (2022)

Concurrent infections by all four dengue virus serotypes during an outbreak of dengue in 2006 in Delhi, India
por: Bharaj, Preeti, et al.
Publicado: (2008)

Meta-Analysis of Dengue Severity during Infection by Different Dengue Virus Serotypes in Primary and Secondary Infections
por: Soo, Kuan-Meng, et al.
Publicado: (2016)

Molecular Surveillance of Dengue in Semarang, Indonesia Revealed the Circulation of an Old Genotype of Dengue Virus Serotype-1
por: Fahri, Sukmal, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_k9rjb877el389e460ogddi8m1h