Cargando…
Structural and Functional Consequences of Circular Permutation on the Active Site of Old Yellow Enzyme
[Image: see text] Circular permutation of the NADPH-dependent oxidoreductase Old Yellow Enzyme from Saccharomyces pastorianus (OYE1) can significantly enhance the enzyme’s catalytic performance. Termini relocation into four regions of the protein (sectors I–IV) near the active site has proven effect...
Autores principales: | Daugherty, Ashley B., Horton, John R., Cheng, Xiaodong, Lutz, Stefan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327928/ https://www.ncbi.nlm.nih.gov/pubmed/25692074 http://dx.doi.org/10.1021/cs501702k |
Ejemplares similares
-
Circular Permutation in Proteins
por: Bliven, Spencer, et al.
Publicado: (2012) -
Equivalence classes of circular codes induced by permutation groups
por: Fayazi, Fariba, et al.
Publicado: (2021) -
Crystal Structure of Circular Permuted RoCBM21 (CP90): Dimerisation and Proximity of Binding Sites
por: Stephen, Preyesh, et al.
Publicado: (2012) -
Structural Analysis of Papain-Like NlpC/P60 Superfamily Enzymes with a Circularly Permuted Topology Reveals Potential Lipid Binding Sites
por: Xu, Qingping, et al.
Publicado: (2011) -
Revealing divergent evolution, identifying circular permutations and detecting active-sites by protein structure comparison
por: Chen, Luonan, et al.
Publicado: (2006)