Four New Sesquiterpenoids from Cultures of the Fungus Phellinidium sulphurascens

Four new sesquiterpenoids, namely 12-hydroxy-3-oxodrimenol (1), 11-hydroxyacetoxydrim-7-en-3β-ol (2), 2,6-dimethyl-7,10-epoxy-10-hydroxymethyldodeca-2,11-dien-6-ol (3), and 7,10-epoxy-2,6,10-trimethyldodeca-2,11-diene-4,6-diol (4), along with fourteen known compounds, were isolated from the cultures...

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Detalles Bibliográficos
Autores principales: Zhao, Zhen-Zhu, Chen, He-Ping, Feng, Tao, Li, Zheng-Hui, Dong, Ze-Jun, Liu, Ji-Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4328000/
https://www.ncbi.nlm.nih.gov/pubmed/25491089
http://dx.doi.org/10.1007/s13659-014-0047-x
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author Zhao, Zhen-Zhu
Chen, He-Ping
Feng, Tao
Li, Zheng-Hui
Dong, Ze-Jun
Liu, Ji-Kai
author_facet Zhao, Zhen-Zhu
Chen, He-Ping
Feng, Tao
Li, Zheng-Hui
Dong, Ze-Jun
Liu, Ji-Kai
author_sort Zhao, Zhen-Zhu
collection PubMed
description Four new sesquiterpenoids, namely 12-hydroxy-3-oxodrimenol (1), 11-hydroxyacetoxydrim-7-en-3β-ol (2), 2,6-dimethyl-7,10-epoxy-10-hydroxymethyldodeca-2,11-dien-6-ol (3), and 7,10-epoxy-2,6,10-trimethyldodeca-2,11-diene-4,6-diol (4), along with fourteen known compounds, were isolated from the cultures of Phellinidium sulphurascens. The structures of compounds 1–4 were established on the basis of extensive spectroscopic analysis. All of them were evaluated for their cytotoxic activities. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s13659-014-0047-x) contains supplementary material, which is available to authorized users.
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spelling pubmed-43280002015-02-19 Four New Sesquiterpenoids from Cultures of the Fungus Phellinidium sulphurascens Zhao, Zhen-Zhu Chen, He-Ping Feng, Tao Li, Zheng-Hui Dong, Ze-Jun Liu, Ji-Kai Nat Prod Bioprospect Original Article Four new sesquiterpenoids, namely 12-hydroxy-3-oxodrimenol (1), 11-hydroxyacetoxydrim-7-en-3β-ol (2), 2,6-dimethyl-7,10-epoxy-10-hydroxymethyldodeca-2,11-dien-6-ol (3), and 7,10-epoxy-2,6,10-trimethyldodeca-2,11-diene-4,6-diol (4), along with fourteen known compounds, were isolated from the cultures of Phellinidium sulphurascens. The structures of compounds 1–4 were established on the basis of extensive spectroscopic analysis. All of them were evaluated for their cytotoxic activities. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s13659-014-0047-x) contains supplementary material, which is available to authorized users. Springer Berlin Heidelberg 2014-12-10 /pmc/articles/PMC4328000/ /pubmed/25491089 http://dx.doi.org/10.1007/s13659-014-0047-x Text en © The Author(s) 2014 https://creativecommons.org/licenses/by/4.0/ This article is published under license to BioMed Central Ltd.Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Original Article
Zhao, Zhen-Zhu
Chen, He-Ping
Feng, Tao
Li, Zheng-Hui
Dong, Ze-Jun
Liu, Ji-Kai
Four New Sesquiterpenoids from Cultures of the Fungus Phellinidium sulphurascens
title Four New Sesquiterpenoids from Cultures of the Fungus Phellinidium sulphurascens
title_full Four New Sesquiterpenoids from Cultures of the Fungus Phellinidium sulphurascens
title_fullStr Four New Sesquiterpenoids from Cultures of the Fungus Phellinidium sulphurascens
title_full_unstemmed Four New Sesquiterpenoids from Cultures of the Fungus Phellinidium sulphurascens
title_short Four New Sesquiterpenoids from Cultures of the Fungus Phellinidium sulphurascens
title_sort four new sesquiterpenoids from cultures of the fungus phellinidium sulphurascens
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4328000/
https://www.ncbi.nlm.nih.gov/pubmed/25491089
http://dx.doi.org/10.1007/s13659-014-0047-x
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