A chimeric EBV gp350/220-based VLP replicates the virion B-cell attachment mechanism and elicits long-lasting neutralizing antibodies in mice

Epstein-Barr virus (EBV), an oncogenic gammaherpesvirus, causes acute infectious mononucleosis (AIM) and is linked to the development of several human malignancies. There is an urgent need for a vaccine that is safe, prevents infection and/or limits disease. Unique among human herpesviruses, glycopr...

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Detalles Bibliográficos
Autores principales: Ogembo, Javier Gordon, Muraswki, Matthew R, McGinnes, Lori W, Parcharidou, Agapi, Sutiwisesak, Rujapak, Tison, Timelia, Avendano, Juan, Agnani, Deep, Finberg, Robert W, Morrison, Trudy G, Fingeroth, Joyce D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4328182/
https://www.ncbi.nlm.nih.gov/pubmed/25885535
http://dx.doi.org/10.1186/s12967-015-0415-2

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