New TB treatments hiding in plain sight

As tuberculosis (TB) toll is revised upward according to the WHO's last estimates, the lack of vaccine strategy and the lengthy antibiotic treatments that unfortunately promote the emergence of drug resistance are a major set back in the fight against this pathogen. In this issue of EMBO Molecu...

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Detalles Bibliográficos
Autores principales: Olive, Andrew J, Sassetti, Christopher M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Closeup
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4328643/
https://www.ncbi.nlm.nih.gov/pubmed/25535253
http://dx.doi.org/10.15252/emmm.201404815
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author Olive, Andrew J
Sassetti, Christopher M
author_facet Olive, Andrew J
Sassetti, Christopher M
author_sort Olive, Andrew J
collection PubMed
description As tuberculosis (TB) toll is revised upward according to the WHO's last estimates, the lack of vaccine strategy and the lengthy antibiotic treatments that unfortunately promote the emergence of drug resistance are a major set back in the fight against this pathogen. In this issue of EMBO Molecular Medicine, Schiebler et al (Mtb) propose a novel and compelling new approach to target Mycobacterium tuberculosis (Mtb) by pharmacologically stimulating intracellular mycobacteria clearance through autophagy.
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spelling pubmed-43286432015-02-17 New TB treatments hiding in plain sight Olive, Andrew J Sassetti, Christopher M EMBO Mol Med Closeup As tuberculosis (TB) toll is revised upward according to the WHO's last estimates, the lack of vaccine strategy and the lengthy antibiotic treatments that unfortunately promote the emergence of drug resistance are a major set back in the fight against this pathogen. In this issue of EMBO Molecular Medicine, Schiebler et al (Mtb) propose a novel and compelling new approach to target Mycobacterium tuberculosis (Mtb) by pharmacologically stimulating intracellular mycobacteria clearance through autophagy. BlackWell Publishing Ltd 2015-02 2014-12-22 /pmc/articles/PMC4328643/ /pubmed/25535253 http://dx.doi.org/10.15252/emmm.201404815 Text en © 2014 The Authors. Published under the terms of the CC BY 4.0 license http://creativecommons.org/licenses/by/4.0/ This is an open access article under the terms of the Creative Commons Attribution 4.0 License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Closeup
Olive, Andrew J
Sassetti, Christopher M
New TB treatments hiding in plain sight
title New TB treatments hiding in plain sight
title_full New TB treatments hiding in plain sight
title_fullStr New TB treatments hiding in plain sight
title_full_unstemmed New TB treatments hiding in plain sight
title_short New TB treatments hiding in plain sight
title_sort new tb treatments hiding in plain sight
topic Closeup
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4328643/
https://www.ncbi.nlm.nih.gov/pubmed/25535253
http://dx.doi.org/10.15252/emmm.201404815
work_keys_str_mv AT oliveandrewj newtbtreatmentshidinginplainsight
AT sassettichristopherm newtbtreatmentshidinginplainsight

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