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The RNA-binding protein Arrest (Bruno) regulates alternative splicing to enable myofibril maturation in Drosophila flight muscle

In Drosophila, fibrillar flight muscles (IFMs) enable flight, while tubular muscles mediate other body movements. Here, we use RNA-sequencing and isoform-specific reporters to show that spalt major (salm) determines fibrillar muscle physiology by regulating transcription and alternative splicing of...

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Detalles Bibliográficos
Autores principales: Spletter, Maria L, Barz, Christiane, Yeroslaviz, Assa, Schönbauer, Cornelia, Ferreira, Irene R S, Sarov, Mihail, Gerlach, Daniel, Stark, Alexander, Habermann, Bianca H, Schnorrer, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4328745/
https://www.ncbi.nlm.nih.gov/pubmed/25532219
http://dx.doi.org/10.15252/embr.201439791