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Antiproliferative and metabolic effects of metformin in a preoperative window clinical trial for endometrial cancer
We conducted a preoperative window study of metformin in endometrial cancer (EC) patients and evaluated its antiproliferative, molecular and metabolic effects. Twenty obese women with endometrioid EC were treated with metformin (850 mg) daily for up to 4 weeks prior to surgical staging. Expression o...
Autores principales: | Schuler, Kevin M, Rambally, Brooke S, DiFurio, Megan J, Sampey, Brante P, Gehrig, Paola A, Makowski, Liza, Bae-Jump, Victoria L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329001/ https://www.ncbi.nlm.nih.gov/pubmed/25417601 http://dx.doi.org/10.1002/cam4.353 |
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