Inhibition of SNW1 association with spliceosomal proteins promotes apoptosis in breast cancer cells

RNA splicing is a fundamental process for protein synthesis. Recent studies have reported that drugs that inhibit splicing have cytotoxic effects on various tumor cell lines. In this report, we demonstrate that depletion of SNW1, a component of the spliceosome, induces apoptosis in breast cancer cel...

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Detalles Bibliográficos
Autores principales: Sato, Naoki, Maeda, Masao, Sugiyama, Mai, Ito, Satoko, Hyodo, Toshinori, Masuda, Akio, Tsunoda, Nobuyuki, Kokuryo, Toshio, Hamaguchi, Michinari, Nagino, Masato, Senga, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329010/
https://www.ncbi.nlm.nih.gov/pubmed/25450007
http://dx.doi.org/10.1002/cam4.366

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