Expression, purification, crystallization, and preliminary X-ray crystallographic studies of the human adiponectin receptors, AdipoR1 and AdipoR2

The adiponectin receptors (AdipoR1 and AdipoR2) are membrane proteins with seven transmembrane helices. These receptors regulate glucose and fatty acid metabolism, thereby ameliorating type 2 diabetes. The full-length human AdipoR1 and a series of N-terminally truncated mutants of human AdipoR1 and...

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Detalles Bibliográficos
Autores principales: Tanabe, Hiroaki, Motoyama, Kanna, Ikeda, Mariko, Wakiyama, Motoaki, Terada, Takaho, Ohsawa, Noboru, Hosaka, Toshiaki, Hato, Masakatsu, Fujii, Yoshifumi, Nakamura, Yoshihiro, Ogasawara, Satoshi, Hino, Tomoya, Murata, Takeshi, Iwata, So, Okada-Iwabu, Miki, Iwabu, Masato, Hirata, Kunio, Kawano, Yoshiaki, Yamamoto, Masaki, Kimura-Someya, Tomomi, Shirouzu, Mikako, Yamauchi, Toshimasa, Kadowaki, Takashi, Yokoyama, Shigeyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329188/
https://www.ncbi.nlm.nih.gov/pubmed/25575462
http://dx.doi.org/10.1007/s10969-014-9192-z

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