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Treatment with AMD3100 attenuates the microglial response and improves outcome after experimental stroke

BACKGROUND: Recovery of lost neurological function after stroke is limited and dependent on multiple mechanisms including inflammatory processes. Selective pharmacological modulation of inflammation might be a promising approach to improve stroke outcome. METHODS: We used 1,1′-[1,4-phenylenebis(meth...

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Detalles Bibliográficos
Autores principales: Walter, Helene L, van der Maten, Gerlinde, Antunes, Ana Rita, Wieloch, Tadeusz, Ruscher, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329193/
https://www.ncbi.nlm.nih.gov/pubmed/25881123
http://dx.doi.org/10.1186/s12974-014-0232-1