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The differential anti-tumour effects of zoledronic acid in breast cancer – evidence for a role of the activin signaling pathway
BACKGROUND: Neo-adjuvant breast cancer clinical trials of zoledronic acid (ZOL) have shown that patients with oestrogen negative (ER-ve) tumours have improved disease outcomes. We investigated the molecular mechanism behind this differential anti-tumour effect according to ER status, hypothesising i...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329195/ https://www.ncbi.nlm.nih.gov/pubmed/25884855 http://dx.doi.org/10.1186/s12885-015-1066-7 |