NEOSCOPE: a randomised Phase II study of induction chemotherapy followed by either oxaliplatin/capecitabine or paclitaxel/carboplatin based chemoradiation as pre-operative regimen for resectable oesophageal adenocarcinoma

BACKGROUND: Both oxaliplatin/capecitabine-based chemoradiation (OXCAP-RT) and carboplatin-paclitaxel based radiation (CarPac-RT) are active regimens in oesophageal adenocarcinoma, but no randomised study has compared their efficacy and toxicity. This randomised phase II “pick a winner” trial will id...

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Detalles Bibliográficos
Autores principales: Mukherjee, Somnath, Hurt, Christopher N, Gwynne, Sarah, Bateman, Andrew, Gollins, Simon, Radhakrishna, Ganesh, Hawkins, Maria, Canham, Jo, Lewis, Wyn, Grabsch, Heike I, Sharma, Ricky A, Wade, Wendy, Maggs, Rhydian, Tranter, Bethan, Roberts, Ashley, Sebag-Montefiore, David, Maughan, Timothy, Griffiths, Gareth, Crosby, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329217/
https://www.ncbi.nlm.nih.gov/pubmed/25880814
http://dx.doi.org/10.1186/s12885-015-1062-y

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