Trogocytosis-mediated expression of HER2 on immune cells may be associated with a pathological complete response to trastuzumab-based primary systemic therapy in HER2-overexpressing breast cancer patients

BACKGROUND: Trogocytosis is defined as the transfer of cell-surface membrane proteins and membrane patches from one cell to another through contact. It is reported that human epidermal growth factor receptor 2 (HER2) could be transferred from cancer cells to monocytes via trogocytosis; however, the...

Descripción completa

Detalles Bibliográficos
Autores principales: Suzuki, Eiji, Kataoka, Tatsuki R, Hirata, Masahiro, Kawaguchi, Kosuke, Nishie, Mariko, Haga, Hironori, Toi, Masakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329225/
https://www.ncbi.nlm.nih.gov/pubmed/25655677
http://dx.doi.org/10.1186/s12885-015-1041-3

Ejemplares similares

Ejemplares similares