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Sphingosine-1-phosphate induces pro-remodelling response in airway smooth muscle cells

BACKGROUND: Increased proliferation of airway smooth muscle (ASM) cells leading to hyperplasia and increased ASM mass is one of the most characteristic features of airway remodelling in asthma. A bioactive lipid, sphingosine-1-phosphate (S1P), has been suggested to affect airway remodelling by stimu...

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Detalles Bibliográficos
Autores principales:	Fuerst, E, Foster, H R, Ward, J P T, Corrigan, C J, Cousins, D J, Woszczek, G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329332/ https://www.ncbi.nlm.nih.gov/pubmed/25041788 http://dx.doi.org/10.1111/all.12489

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