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Characterizing alpha helical properties of Ebola viral proteins as potential targets for inhibition of alpha-helix mediated protein-protein interactions

Ebola, considered till recently as a rare and endemic disease, has dramatically transformed into a potentially global humanitarian crisis. The genome of Ebola, a member of the Filoviridae family, encodes seven proteins. Based on the recently implemented software (PAGAL) for analyzing the hydrophobic...

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Detalles Bibliográficos
Autores principales: Chakraborty, Sandeep, Rao, Basuthkar J., Asgeirsson, Bjarni, Dandekar, Abhaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329671/
https://www.ncbi.nlm.nih.gov/pubmed/25717367
http://dx.doi.org/10.12688/f1000research.5573.3