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Histone deacetylase inhibition as an alternative strategy against invasive aspergillosis

Invasive aspergillosis (IA) is a life-threatening infection due to Aspergillus fumigatus and other Aspergillus spp. Drugs targeting the fungal cell membrane (triazoles, amphotericin B) or cell wall (echinocandins) are currently the sole therapeutic options against IA. Their limited efficacy and the...

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Detalles Bibliográficos
Autores principales: Lamoth, Frédéric, Juvvadi, Praveen R., Steinbach, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329796/
https://www.ncbi.nlm.nih.gov/pubmed/25762988
http://dx.doi.org/10.3389/fmicb.2015.00096