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PTEN: Multiple Functions in Human Malignant Tumors

PTEN is the most important negative regulator of the PI3K signaling pathway. In addition to its canonical, PI3K inhibition-dependent functions, PTEN can also function as a tumor suppressor in a PI3K-independent manner. Indeed, the PTEN network regulates a broad spectrum of biological functions, modu...

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Detalles Bibliográficos
Autores principales:	Milella, Michele, Falcone, Italia, Conciatori, Fabiana, Cesta Incani, Ursula, Del Curatolo, Anais, Inzerilli, Nicola, Nuzzo, Carmen M. A., Vaccaro, Vanja, Vari, Sabrina, Cognetti, Francesco, Ciuffreda, Ludovica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329810/ https://www.ncbi.nlm.nih.gov/pubmed/25763354 http://dx.doi.org/10.3389/fonc.2015.00024

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