Clinical utility of eslicarbazepine: current evidence

Eslicarbazepine acetate (ESL) is a new antiepileptic drug whose mechanism of action is blockade of the voltage-gated sodium channel (VGSC). However, in respect to carbamazepine and oxcarbazepine, the active ESL metabolite (eslicarbazepine) affects slow inactivation of VGSC and has a similar affinity...

Descripción completa

Detalles Bibliográficos
Autores principales: Zaccara, Gaetano, Giovannelli, Fabio, Cincotta, Massimo, Carelli, Alessia, Verrotti, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330027/
https://www.ncbi.nlm.nih.gov/pubmed/25709402
http://dx.doi.org/10.2147/DDDT.S57409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330027/
https://www.ncbi.nlm.nih.gov/pubmed/25709402
http://dx.doi.org/10.2147/DDDT.S57409

Ejemplares similares