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A systematic survey of the Cys(2)His(2) zinc finger DNA-binding landscape

Cys(2)His(2) zinc fingers (C2H2-ZFs) comprise the largest class of metazoan DNA-binding domains. Despite this domain's well-defined DNA-recognition interface, and its successful use in the design of chimeric proteins capable of targeting genomic regions of interest, much remains unknown about i...

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Detalles Bibliográficos
Autores principales:	Persikov, Anton V., Wetzel, Joshua L., Rowland, Elizabeth F., Oakes, Benjamin L., Xu, Denise J., Singh, Mona, Noyes, Marcus B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Synthetic Biology and Bioengineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330361/ https://www.ncbi.nlm.nih.gov/pubmed/25593323 http://dx.doi.org/10.1093/nar/gku1395

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