Sequences spanning the leader-repeat junction mediate CRISPR adaptation to phage in Streptococcus thermophilus

CRISPR-Cas systems are RNA-based immune systems that protect prokaryotes from invaders such as phages and plasmids. In adaptation, the initial phase of the immune response, short foreign DNA fragments are captured and integrated into host CRISPR loci to provide heritable defense against encountered...

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Detalles Bibliográficos
Autores principales: Wei, Yunzhou, Chesne, Megan T., Terns, Rebecca M., Terns, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330368/
https://www.ncbi.nlm.nih.gov/pubmed/25589547
http://dx.doi.org/10.1093/nar/gku1407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330368/
https://www.ncbi.nlm.nih.gov/pubmed/25589547
http://dx.doi.org/10.1093/nar/gku1407

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