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Development of a unique epigenetic signature during in vivo Th17 differentiation

Activated naive CD4(+) T cells are highly plastic cells that can differentiate into various T helper (Th) cell fates characterized by the expression of effector cytokines like IFN-γ (Th1), IL-4 (Th2) or IL-17A (Th17). Although previous studies have demonstrated that epigenetic mechanisms including D...

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Detalles Bibliográficos
Autores principales: Yang, Bi-Huei, Floess, Stefan, Hagemann, Stefanie, Deyneko, Igor V., Groebe, Lothar, Pezoldt, Joern, Sparwasser, Tim, Lochner, Matthias, Huehn, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330377/
https://www.ncbi.nlm.nih.gov/pubmed/25593324
http://dx.doi.org/10.1093/nar/gkv014

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