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Engineered ribosomal RNA operon copy-number variants of E. coli reveal the evolutionary trade-offs shaping rRNA operon number
Ribosomal RNA (rrn) operons, characteristically present in several copies in bacterial genomes (7 in E. coli), play a central role in cellular physiology. We investigated the factors determining the optimal number of rrn operons in E. coli by constructing isogenic variants with 5–10 operons. We foun...
Autores principales: | Gyorfy, Zsuzsanna, Draskovits, Gabor, Vernyik, Viktor, Blattner, Frederick F., Gaal, Tamas, Posfai, Gyorgy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330394/ https://www.ncbi.nlm.nih.gov/pubmed/25618851 http://dx.doi.org/10.1093/nar/gkv040 |
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