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Accurate transcriptome-wide prediction of microRNA targets and small interfering RNA off-targets with MIRZA-G

Small interfering RNA (siRNA)-mediated knock-down is a widely used experimental approach to characterizing gene function. Although siRNAs are designed to guide the cleavage of perfectly complementary mRNA targets, acting similarly to microRNAs (miRNAs), siRNAs down-regulate the expression of hundred...

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Detalles Bibliográficos
Autores principales: Gumienny, Rafal, Zavolan, Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330396/
https://www.ncbi.nlm.nih.gov/pubmed/25628353
http://dx.doi.org/10.1093/nar/gkv050