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Accurate transcriptome-wide prediction of microRNA targets and small interfering RNA off-targets with MIRZA-G
Small interfering RNA (siRNA)-mediated knock-down is a widely used experimental approach to characterizing gene function. Although siRNAs are designed to guide the cleavage of perfectly complementary mRNA targets, acting similarly to microRNAs (miRNAs), siRNAs down-regulate the expression of hundred...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330396/ https://www.ncbi.nlm.nih.gov/pubmed/25628353 http://dx.doi.org/10.1093/nar/gkv050 |