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P70S6K and Elf4E Dual Inhibition Is Essential to Control Bladder Tumor Growth and Progression in Orthotopic Mouse Non-muscle Invasive Bladder Tumor Model

We investigated how the dual inhibition of the molecular mechanism of the mammalian target of the rapamycin (mTOR) downstreams, P70S6 kinase (P70S6K) and eukaryotic initiation factor 4E (eIF4E), can lead to a suppression of the proliferation and progression of urothelial carcinoma (UC) in an orthoto...

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Detalles Bibliográficos
Autores principales:	Chi, Byung Hoon, Kim, Soon-Ja, Seo, Ho Kyung, Seo, Hye-Hyun, Lee, Sang-Jin, Kwon, Jong Kyou, Lee, Tae-Jin, Chang, In Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Academy of Medical Sciences 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330487/ https://www.ncbi.nlm.nih.gov/pubmed/25729255 http://dx.doi.org/10.3346/jkms.2015.30.3.308

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