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Toll-like receptor-2 deficiency induces schizophrenia-like behaviors in mice

Dysregulation of the immune system contributes to the pathogenesis of neuropsychiatric disorders including schizophrenia. Here, we demonstrated that toll-like receptor (TLR)-2, a family of pattern-recognition receptors, is involved in the pathogenesis of schizophrenia-like symptoms. Psychotic sympto...

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Detalles Bibliográficos
Autores principales: Park, Se Jin, Lee, Jee Youn, Kim, Sang Jeong, Choi, Se-Young, Yune, Tae Young, Ryu, Jong Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330527/
https://www.ncbi.nlm.nih.gov/pubmed/25687169
http://dx.doi.org/10.1038/srep08502