Insights into the Role of Substrates on the Interaction between Cytochrome b(5) and Cytochrome P450 2B4 by NMR

Mammalian cytochrome b(5) (cyt b(5)) is a membrane-bound protein capable of donating an electron to cytochrome P450 (P450) in the P450 catalytic cycle. The interaction between cyt b(5) and P450 has been reported to be affected by the substrates of P450; however, the mechanism of substrate modulation...

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Detalles Bibliográficos
Autores principales: Zhang, Meng, Le Clair, Stéphanie V., Huang, Rui, Ahuja, Shivani, Im, Sang-Choul, Waskell, Lucy, Ramamoorthy, Ayyalusamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330534/
https://www.ncbi.nlm.nih.gov/pubmed/25687717
http://dx.doi.org/10.1038/srep08392

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