Impact of Sox9 Dosage and Hes1-mediated Notch Signaling in Controlling the Plasticity of Adult Pancreatic Duct Cells in Mice

In the adult pancreas, there has been a long-standing dispute as to whether stem/precursor populations that retain plasticity to differentiate into endocrine or acinar cell types exist in ducts. We previously reported that adult Sox9-expressing duct cells are sufficiently plastic to supply new acina...

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Detalles Bibliográficos
Autores principales: Hosokawa, Shinichi, Furuyama, Kenichiro, Horiguchi, Masashi, Aoyama, Yoshiki, Tsuboi, Kunihiko, Sakikubo, Morito, Goto, Toshihiko, Hirata, Koji, Tanabe, Wataru, Nakano, Yasuhiro, Akiyama, Haruhiko, Kageyama, Ryoichiro, Uemoto, Shinji, Kawaguchi, Yoshiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330537/
https://www.ncbi.nlm.nih.gov/pubmed/25687338
http://dx.doi.org/10.1038/srep08518

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