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Three-dimensional quantitative structure-activity relationships and docking studies of some structurally diverse flavonoids and design of new aldose reductase inhibitors

Aldose reductase (AR) plays an important role in the development of several long-term diabetic complications. Inhibition of AR activities is a strategy for controlling complications arising from chronic diabetes. Several AR inhibitors have been reported in the literature. Flavonoid type compounds ar...

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Detalles Bibliográficos
Autores principales: Chandra De, Utpal, Debnath, Tanusree, Sen, Debanjan, Debnath, Sudhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330605/
https://www.ncbi.nlm.nih.gov/pubmed/25709964
http://dx.doi.org/10.4103/2231-4040.150366