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Treatment with a sphingosine analog after the inception of house dust mite-induced airway inflammation alleviates key features of experimental asthma

BACKGROUND: In vivo phosphorylation of sphingosine analogs with their ensuing binding and activation of their cell-surface sphingosine-1-phosphate receptors is regarded as the main immunomodulatory mechanism of this new class of drugs. Prophylactic treatment with sphingosine analogs interferes with...

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Detalles Bibliográficos
Autores principales:	Gendron, David, Lemay, Anne-Marie, Tremblay, Claudine, Lai, Laetitia JA, Langlois, Anick, Bernatchez, Émilie, Flamand, Nicolas, Blanchet, Marie-Renée, Don, Anthony S, Bossé, Ynuk, Bissonnette, Élyse, Marsolais, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330646/ https://www.ncbi.nlm.nih.gov/pubmed/25645346 http://dx.doi.org/10.1186/s12931-015-0180-z

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