An investigation of gene-gene interactions in dose-response studies with Bayesian nonparametrics

BACKGROUND: Best practice for statistical methodology in cell-based dose-response studies has yet to be established. We examine the ability of MANOVA to detect trait-associated genetic loci in the presence of gene-gene interactions. We present a novel Bayesian nonparametric method designed to detect...

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Detalles Bibliográficos
Autores principales: Beam, Andrew L, Motsinger-Reif, Alison A, Doyle, Jon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330980/
https://www.ncbi.nlm.nih.gov/pubmed/25691918
http://dx.doi.org/10.1186/s13040-015-0039-3

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