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Rotational thrombelastometry: a step forward to safer patient care?

The study by Hincker and colleagues indicated that the perioperative use of rotational thrombelastometry (ROTEM™) could predict thromboembolic events in 90% of the cases in non-cardiac surgery. Viscoelastic tests (VETs) - ROTEM™ and thrombelastography (TEG™) - are used mainly to predict bleeding com...

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Autor principal: Saner, Fuat H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331150/
https://www.ncbi.nlm.nih.gov/pubmed/25672525
http://dx.doi.org/10.1186/s13054-014-0706-7
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author Saner, Fuat H
author_facet Saner, Fuat H
author_sort Saner, Fuat H
collection PubMed
description The study by Hincker and colleagues indicated that the perioperative use of rotational thrombelastometry (ROTEM™) could predict thromboembolic events in 90% of the cases in non-cardiac surgery. Viscoelastic tests (VETs) - ROTEM™ and thrombelastography (TEG™) - are used mainly to predict bleeding complications. Most conventional coagulation tests, like prothrombin time and activated partial thromboplastin time, can identify a disturbance in plasmatic hemostasis. However, the relevance of these assays is limited to the initiation phase of coagulation, whereas VETs are designed to assess the whole clotting kinetics and strength of the whole blood clot and reflect more the interaction between procoagulants, anticoagulants, and platelets. The first reports about VET and hypercoagulable state were published more than 25 years ago. Since then, several studies with different quality and sample size have been published, sometimes with conflicting results. A systematic review about hypercoagulable state and TEG™ indicated that further studies are needed to recommend VETs as a screening tool to predict postoperative thrombosis.
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spelling pubmed-43311502015-02-18 Rotational thrombelastometry: a step forward to safer patient care? Saner, Fuat H Crit Care Commentary The study by Hincker and colleagues indicated that the perioperative use of rotational thrombelastometry (ROTEM™) could predict thromboembolic events in 90% of the cases in non-cardiac surgery. Viscoelastic tests (VETs) - ROTEM™ and thrombelastography (TEG™) - are used mainly to predict bleeding complications. Most conventional coagulation tests, like prothrombin time and activated partial thromboplastin time, can identify a disturbance in plasmatic hemostasis. However, the relevance of these assays is limited to the initiation phase of coagulation, whereas VETs are designed to assess the whole clotting kinetics and strength of the whole blood clot and reflect more the interaction between procoagulants, anticoagulants, and platelets. The first reports about VET and hypercoagulable state were published more than 25 years ago. Since then, several studies with different quality and sample size have been published, sometimes with conflicting results. A systematic review about hypercoagulable state and TEG™ indicated that further studies are needed to recommend VETs as a screening tool to predict postoperative thrombosis. BioMed Central 2014-12-26 2014 /pmc/articles/PMC4331150/ /pubmed/25672525 http://dx.doi.org/10.1186/s13054-014-0706-7 Text en © Saner; licensee BioMed Central Ltd. 2014 The licensee has exclusive rights to distribute this article, in any medium, for 12 months following its publication. After this time, the article is available under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Commentary
Saner, Fuat H
Rotational thrombelastometry: a step forward to safer patient care?
title Rotational thrombelastometry: a step forward to safer patient care?
title_full Rotational thrombelastometry: a step forward to safer patient care?
title_fullStr Rotational thrombelastometry: a step forward to safer patient care?
title_full_unstemmed Rotational thrombelastometry: a step forward to safer patient care?
title_short Rotational thrombelastometry: a step forward to safer patient care?
title_sort rotational thrombelastometry: a step forward to safer patient care?
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331150/
https://www.ncbi.nlm.nih.gov/pubmed/25672525
http://dx.doi.org/10.1186/s13054-014-0706-7
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