In Vitro Inhibitory and Cytotoxic Activity of MFM 501, a Novel Codonopsinine Derivative, against Methicillin-Resistant Staphylococcus aureus Clinical Isolates

28 new pyrrolidine types of compounds as analogues for natural polyhydroxy alkaloids of codonopsinine were evaluated for their anti-MRSA activity using MIC and MBC value determination assay against a panel of S. aureus isolates. One pyrrolidine compound, MFM 501, exhibited good inhibitory activity w...

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Detalles Bibliográficos
Autores principales: Johari, Saiful Azmi, Mohtar, Mastura, Syed Mohammad, Sharifah Aminah, Sahdan, Rohana, Shaameri, Zurina, Hamzah, Ahmad Sazali, Mohammat, Mohd Fazli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331153/
https://www.ncbi.nlm.nih.gov/pubmed/25710030
http://dx.doi.org/10.1155/2015/823829

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