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A Potential Epigenetic Marker Mediating Serum Folate and Vitamin B(12) Levels Contributes to the Risk of Ischemic Stroke

Stroke is a multifactorial disease that may be associated with aberrant DNA methylation profiles. We investigated epigenetic dysregulation for the methylenetetrahydrofolate reductase (MTHFR) gene among ischemic stroke patients. Cases and controls were recruited after obtaining signed written informe...

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Detalles Bibliográficos
Autores principales: Keat Wei, Loo, Sutherland, Heidi, Au, Anthony, Camilleri, Emily, Haupt, Larisa M., Gan, Siew Hua, Griffiths, Lyn R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331165/
https://www.ncbi.nlm.nih.gov/pubmed/25705649
http://dx.doi.org/10.1155/2015/167976