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The ER Stress-Mediated Mitochondrial Apoptotic Pathway and MAPKs Modulate Tachypacing-Induced Apoptosis in HL-1 Atrial Myocytes
BACKGROUND AND OBJECT: Cell apoptosis is a contributing factor in the initiation, progression and relapse of atrial fibrillation (AF), a life-threatening illness accompanied with stroke and heart failure. However, the regulatory cascade of apoptosis is intricate and remains unidentified, especially...
Autores principales: | Shi, Jiaojiao, Jiang, Qi, Ding, Xiangwei, Xu, Wenhua, Wang, Dao W., Chen, Minglong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331367/ https://www.ncbi.nlm.nih.gov/pubmed/25689866 http://dx.doi.org/10.1371/journal.pone.0117567 |
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