The early antibiotic therapy in septic patients - milestone or sticking point?

Sepsis is one of the oldest and most elusive syndromes in medicine. Every effort should be made to treat these patients with the best available evidence. As a milestone, empiric antimicrobial therapy is essential in order to reduce morbidity and mortality of septic patients. As a sticking point, the...

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Detalles Bibliográficos
Autores principales: Bernhard, Michael, Lichtenstern, Christoph, Eckmann, Christian, Weigand, Markus A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331420/
https://www.ncbi.nlm.nih.gov/pubmed/25672873
http://dx.doi.org/10.1186/s13054-014-0671-1
Descripción
Sumario:Sepsis is one of the oldest and most elusive syndromes in medicine. Every effort should be made to treat these patients with the best available evidence. As a milestone, empiric antimicrobial therapy is essential in order to reduce morbidity and mortality of septic patients. As a sticking point, the use of broad-spectrum antimicrobial agents may be associated with induction of resistance among common pathogens.

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